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目次 |
SECTION I For Students of Diagnostic Radiology, Nuclear Medicine, and Radiation Oncology 1 1 Physics and Chemistry of Radiation Absorption 2 2 Molecular Mechanisms of DNA and Chromosome Damage and Repair 11 3 Cell Survival Curves 35 4 Radiosensitivity and Cell Age in the Mitotic Cycle 54 5 Fractionated Radiation and the Dose-Rate Effect 67 6 Oxygen Effect and Reoxygenation 82 7 Linear Energy Transfer and Relative Biologic Effectiveness 101 8 Acute Radiation Syndrome 111 9 Medical Countermeasures to Radiation Exposure 126 10 Radiation Carcinogenesis 135 11 Heritable Effects of Radiation 162 12 Effects of Radiation on the Embryo and Fetus 177 13 Radiation Cataractogenesis 191 14 Radiologic Terrorism 197 15 Doses and Risks in Diagnostic Radiology, Interventional Radiology and Cardiology, and Nuclear Medicine 206 16 Radiation Protection 237 SECTION II For Students of Radiation Oncology 257 17 Molecular Techniques in Radiobiology 258 18 Cancer Biology 295 19 Dose–Response Relationships for Model Normal Tissues 327 20 Clinical Response of Normal Tissues 351 21 Model Tumor Systems 380 22 Cell, Tissue, and Tumor Kinetics 398 23 Time, Dose, and Fractionation in Radiotherapy 417 24 Retreatment after Radiotherapy: The Possibilities and the Perils 437 25 Alternative Radiation Modalities 444 26 The Biology and Exploitation of Tumor Hypoxia 458 27 Chemotherapeutic Agents from the Perspective of the Radiation Biologist 475 28 Hyperthermia 516 Glossary 534 Index 564 |
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